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Yes, amoeba is playable

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Found in the following dictionaries

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SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Amoeba" Definition

noun

Any of various one-celled aquatic or parasitic protozoans of the genus Amoeba or related genera, having no definite form and consisting of a mass of protoplasm containing one or more nuclei surrounded by a flexible outer membrane. It moves by means of pseudopods.
Any of a large genus () of naked rhizopod protozoans with lobed and never anastomosing pseudopodia, without permanent organelles or supporting structures, and of wide distribution in fresh and salt water and moist terrestrial environments.
A naked rhizopod or other protozoan.
A single-celled animal that catches food and moves about by extending fingerlike projections of protoplasm. Amoebas are either free-living in damp environments or parasitic.
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