Yes, defis is in the scrabble dictionary

...and is worth 9 points by itself.

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Defis Definition

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Here are some other words you could make with the letters DEFIS, you can also
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Top Words by points	Points
defis	9

2 letter words with DEFIS	Points
de	3
si	2
is	2
if	5
id	3
ed	3
ef	5
es	2
fe	5

3 letter words with DEFIS	Points
def	7
sei	3
ifs	6
ids	4
fie	6
fid	7
fes	6
fed	7
efs	6
eds	4
dis	4
dif	7
die	4

4 letter words with DEFIS	Points
feds	8
fids	8
difs	8
dies	5
desi	5
defi	8
ides	5
seif	7
side	5

5 letter words with DEFIS	Points
defis	9

Found 32 words in 0.14371 seconds