Scrabble Dictionary

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Yes, denature is playable

...and is worth 11 points.

Found in the following dictionaries

Enable (Words with friends)
SOWPODS (Collins Scrabble Words)
OTCWL2014 (NASPA Word List 2014)
TWL06 (NASPA List 2006)

"Denature" Definition

verb-transitive

Biochemistry To cause the paired strands of (double-stranded DNA) to separate into individual single strands.
Biochemistry To cause the tertiary structure of (a protein) to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.
Physics To add nonfissionable matter to (fissionable material) so as to prevent use in an atomic weapon.
To change the nature or natural qualities of.
To render unfit to eat or drink without destroying usefulness in other applications, especially to add methanol to (ethyl alcohol).

verb

to deprive of natural qualities change the nature of as.
To make (alcohol) unfit for drinking (as by adding an obnoxious substance) without impairing usefulness for other purposes.
To modify the molecular structure of (as a protein or DNA) especially by heat, acid, alkali, or ultraviolet radiation so as to destroy or diminish some of the original properties and especially the specific biological activity .
To become .
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