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Yes, duo is in the scrabble dictionary

...and is worth 5 points by itself.

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Duo Definition

noun

Music A duet, especially two performers singing or playing together.
from The American Heritage Dictionary of the English Language, 4th Edition
Two people or two things in close association: a duo of negotiators.
from The American Heritage Dictionary of the English Language, 4th Edition

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Top Words by points

Points
duo

4

2 letter words with DUO

Points

do

3

od

3

3 letter words with DUO

Points

duo

4

oud

4

udo

4

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