Yes, dupion is in the scrabble dictionary

...and is worth 12 points by itself.

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Dupion Definition

noun

A double cocoon, made by two silkworms.
from the English-language Wiktionary
A double cocoon formed by two silkworms spinning together.
from The Century Dictionary and Cyclopedia
The coarse silk furnished by such double cocoons.
from The Century Dictionary and Cyclopedia

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Top Words by points

Points

dupion

9

2 letter words with DUPION

Points

in

2

pi

4

op

4

on

2

oi

2

od

3

po

4

nu

2

no

2

id

3

un

2

up

4

do

3

3 letter words with DUPION

Points

poi

5

din

4

pod

6

pud

6

pun

5

piu

5

pin

5

udo

4

uni

3

upo

5

nod

4

nip

5

ion

3

dip

6

dup

6

don

4

dui

4

dun

4

oud

4

duo

4

4 letter words with DUPION

Points

pond

7

undo

5

udon

5

updo

7

pion

6

dino

5

upon

6

nodi

5

5 letter words with DUPION

Points

pound

8

poind

8

6 letter words with DUPION

Points

dupion

9

unipod

9

Found 45 words in 0.20843 seconds