Yes, isle is in the scrabble dictionary

...and is worth 5 points by itself.

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Isle Definition

noun

An island, especially a small one.
from The American Heritage Dictionary of the English Language, 4th Edition

verb

To make an isle of.
from Free Scrabble Dictionary
To place on or as if on an isle.
from Free Scrabble Dictionary

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Top Words by points

Points

isle

4

2 letter words with ISLE

Points

el

2

es

2

is

2

li

2

si

2

3 letter words with ISLE

Points

els

3

lei

3

lie

3

lis

3

sei

3

sel

3

4 letter words with ISLE

Points

isle

4

leis

4

lies

4

Found 14 words in 0.14929 seconds