Yes, lesion is in the scrabble dictionary

...and is worth 8 points by itself.

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Lesion Definition

noun

A localized pathological change in a bodily organ or tissue.
from The American Heritage Dictionary of the English Language, 4th Edition
A wound or injury.
from The American Heritage Dictionary of the English Language, 4th Edition
An infected or diseased patch of skin.
from The American Heritage Dictionary of the English Language, 4th Edition
An abnormal change in structure of an organ or part due to injury or disease.
from Free Scrabble Dictionary
One that is circumscribed and well defined.
from Free Scrabble Dictionary

verb-transitive

To cause a lesion to form on or in.
from The American Heritage Dictionary of the English Language, 4th Edition

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Top Words by points

Points

lesion

6

2 letter words with LESION

Points

en

2

ne

2

no

2

so

2

si

2

oe

2

oi

2

on

2

os

2

lo

2

li

2

is

2

in

2

es

2

el

2

3 letter words with LESION

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one

3

sel

3

sen

3

sin

3

sol

3

son

3

nil

3

nos

3

sei

3

els

3

ens

3

eon

3

lis

3

lin

3

lie

3

ins

3

ion

3

ole

3

oil

3

oes

3

lei

3

ose

3

ons

3

4 letter words with LESION

Points

nils

4

ones

4

oles

4

noel

4

noes

4

noil

4

nose

4

oils

4

sine

4

enol

4

eons

4

sone

4

soli

4

sole

4

ions

4

isle

4

soil

4

leis

4

leno

4

lens

4

lien

4

lies

4

line

4

lino

4

lins

4

lion

4

loin

4

lone

4

lose

4

sloe

4

silo

4

5 letter words with LESION

Points

solei

5

lines

5

eloin

5

enols

5

eosin

5

lenis

5

lenos

5

liens

5

olein

5

linos

5

lions

5

loins

5

noels

5

noils

5

noise

5

6 letter words with LESION

Points

lesion

6

insole

6

eloins

6

oleins

6

Found 88 words in 0.1852 seconds