Yes, lexis is in the scrabble dictionary

...and is worth 13 points by itself.

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Lexis Definition

noun

The total set of words in a language as distinct from morphology; vocabulary.
from The American Heritage Dictionary of the English Language, 4th Edition

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Top Words by points

Points

lexis

12

2 letter words with LEXIS

Points

es

2

ex

9

el

2

is

2

xi

9

li

2

si

2

3 letter words with LEXIS

Points

xis

10

six

10

sex

10

sel

3

sei

3

lis

3

lie

3

lex

10

lei

3

els

3

4 letter words with LEXIS

Points

leis

4

lies

4

isle

4

ilex

11

5 letter words with LEXIS

Points

lexis

12

silex

12

Found 23 words in 0.13842 seconds