Yes, loco is in the scrabble dictionary

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Loco Definition

noun

See loco disease.
from The American Heritage Dictionary of the English Language, 4th Edition
See locoweed.
from The American Heritage Dictionary of the English Language, 4th Edition
A locomotive:.
from Free Scrabble Dictionary

verb

To poison with.
from Free Scrabble Dictionary
To make frenzied or crazy.
from Free Scrabble Dictionary

adverb

Music At the pitch written. Used chiefly as a direction.
from The American Heritage Dictionary of the English Language, 4th Edition

adjective

Slang Mad; insane.
from The American Heritage Dictionary of the English Language, 4th Edition
Mentally disordered.
from Free Scrabble Dictionary
Crazy.
from Free Scrabble Dictionary

verb-transitive

Slang To make insane; craze.
from The American Heritage Dictionary of the English Language, 4th Edition
To poison with locoweed.
from The American Heritage Dictionary of the English Language, 4th Edition

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Top Words by points

Points

cool

6

2 letter words with LOCO

Points

lo

2

3 letter words with LOCO

Points

col

5

coo

5

loo

3

4 letter words with LOCO

Points

cool

6

loco

6

Found 6 words in 0.16307 seconds