Yes, lyssa is in the scrabble dictionary

...and is worth 8 points by itself.

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Lyssa Definition

noun

Hydrophobia.
from the GNU version of the Collaborative International Dictionary of English

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Here are some other words you could make with the letters LYSSA, you can also
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Top Words by points

Points

lassy

8

2 letter words with LYSSA

Points

as

2

ay

5

al

2

ya

5

la

2

3 letter words with LYSSA

Points

yas

6

sly

6

say

6

sal

3

lay

6

las

3

ays

6

ass

3

als

3

4 letter words with LYSSA

Points

lass

4

lays

7

sals

4

says

7

slay

7

5 letter words with LYSSA

Points

lassy

8

lyssa

8

slays

8

Found 22 words in 0.13173 seconds