Yes, mesne is in the scrabble dictionary

...and is worth 9 points by itself.

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Mesne Definition

noun

Intermediate.
from the English-language Wiktionary

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Top Words by points

Points

semen

7

2 letter words with MESNE

Points

en

2

ne

2

em

4

me

4

es

2

3 letter words with MESNE

Points

ems

5

ens

3

eme

5

men

5

nee

3

see

3

sen

3

4 letter words with MESNE

Points

emes

6

esne

4

sene

4

neem

6

seme

6

seem

6

seen

4

5 letter words with MESNE

Points

semen

7

neems

7

mesne

7

mense

7

Found 23 words in 0.14023 seconds