Yes, nisus is in the scrabble dictionary

...and is worth 7 points by itself.

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Nisus Definition

noun

An effort or endeavor to realize an aim.
from The American Heritage Dictionary of the English Language, 4th Edition
A mental or physical effort to attain an end a perfective urge or endeavor.
from Free Scrabble Dictionary

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Top Words by points

Points

sinus

5

2 letter words with NISUS

Points

is

2

nu

2

us

2

si

2

un

2

in

2

3 letter words with NISUS

Points

sun

3

uns

3

uni

3

sus

3

sis

3

sin

3

nus

3

ins

3

4 letter words with NISUS

Points

sins

4

suns

4

unis

4

5 letter words with NISUS

Points

sinus

5

nisus

5

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