Yes, node is in the scrabble dictionary

...and is worth 6 points by itself.

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Node Definition

noun

A knob, knot, protuberance, or swelling.
Astronomy Either of two diametrically opposite points at which the orbit of a planet intersects the ecliptic.
Astronomy Either of two points at which the orbit of a satellite intersects the orbital plane of a planet.
Botany The point on a stem where a leaf is attached or has been attached; a joint.
Computer Science A terminal in a computer network.

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Here are some other words you could make with the letters NODE

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Top Words by points

Points

node

5

2 letter words with NODE

Points

do

3

de

3

on

2

oe

2

ed

3

en

2

od

3

ne

2

no

2

3 letter words with NODE

Points

one

3

ode

4

nod

4

eon

3

end

4

don

4

doe

4

den

4

4 letter words with NODE

Points

node

5

done

5

Found 19 words in 0.14873 seconds