Yes, once is in the scrabble dictionary

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Once Definition

noun

A single occurrence; one time: Once will have to do. You can go just this once.
from The American Heritage Dictionary of the English Language, 4th Edition
One single time one time at least .
from Free Scrabble Dictionary

conjunction

As soon as; if ever; when: Once he goes, we can clean up.
from The American Heritage Dictionary of the English Language, 4th Edition
At the moment when .
from Free Scrabble Dictionary

adverb

At any time; ever: Once known, his face is never forgotten.
from The American Heritage Dictionary of the English Language, 4th Edition
At one time in the past; formerly.
from The American Heritage Dictionary of the English Language, 4th Edition
By one degree of relationship: my first cousin once removed.
from The American Heritage Dictionary of the English Language, 4th Edition
One time only: once a day.
from The American Heritage Dictionary of the English Language, 4th Edition
One time and no more .
from Free Scrabble Dictionary

idiom

At once All at one time; simultaneously: Everything happened at once. The view of the skyline is at once awesome, grand, and disappointing.
from The American Heritage Dictionary of the English Language, 4th Edition
At once Immediately; instantly: Leave the room at once.
from The American Heritage Dictionary of the English Language, 4th Edition

adjective

Having been formerly; former: the once capital of the nation.
from The American Heritage Dictionary of the English Language, 4th Edition
That once was .
from Free Scrabble Dictionary

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Top Words by points

Points

cone

6

2 letter words with ONCE

Points

en

2

ne

2

no

2

oe

2

on

2

3 letter words with ONCE

Points

con

5

eco

5

eon

3

one

3

4 letter words with ONCE

Points

cone

6

once

6

Found 11 words in 0.11546 seconds