Yes, optimise is in the scrabble dictionary

...and is worth 14 points by itself.

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Optimise Definition

verb

Alternative spelling of optimize.
from the English-language Wiktionary

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Top Words by points

Points

optimise

12

2 letter words with OPTIMISE

Points

em

4

es

2

et

2

is

2

it

2

me

4

mi

4

mo

4

oe

2

oi

2

om

4

op

4

os

2

pe

4

pi

4

po

4

si

2

so

2

te

2

ti

2

to

2

3 letter words with OPTIMISE

Points

emo

5

ems

5

est

3

imp

7

ism

5

its

3

met

5

mis

5

moi

5

mop

7

mos

5

mot

5

oes

3

oms

5

ope

5

ops

5

opt

5

ose

3

pes

5

pet

5

pie

5

pis

5

pit

5

poi

5

pom

7

pos

5

pot

5

psi

5

pst

5

sei

3

set

3

sim

5

sip

5

sit

3

som

5

sop

5

sot

3

tes

3

tie

3

tip

5

tis

3

toe

3

tom

5

top

5

4 letter words with OPTIMISE

Points

emit

6

emos

6

epos

6

impi

8

imps

8

item

6

mise

6

miso

6

mist

6

mite

6

mope

8

mops

8

most

6

mote

6

mots

6

omit

6

opes

6

opts

6

peso

6

pest

6

pets

6

pies

6

piso

6

pits

6

poem

8

poet

6

pois

6

pome

8

poms

8

pose

6

post

6

pots

6

semi

6

sept

6

simp

8

sipe

6

site

4

smit

6

some

6

spit

6

spot

6

stem

6

step

6

stim

6

stop

6

temp

8

ties

4

time

6

tipi

6

tips

6

toes

4

tome

6

toms

6

tope

6

topi

6

tops

6

5 letter words with OPTIMISE

Points

emits

7

estop

7

impis

9

items

7

metis

7

mites

7

mitis

7

moist

7

mopes

9

moste

7

motes

7

omits

7

pesto

7

piste

7

poems

9

poets

7

poise

7

pomes

9

posit

7

smite

7

smote

7

spite

7

stime

7

stipe

7

stomp

9

stope

7

tempi

9

tempo

9

temps

9

times

7

tipis

7

tomes

7

topes

7

topis

7

6 letter words with OPTIMISE

Points

impose

10

impost

10

optime

10

pities

8

postie

8

potsie

8

somite

8

sopite

8

tempos

10

7 letter words with OPTIMISE

Points

mopiest

11

optimes

11

pietism

11

8 letter words with OPTIMISE

Points

optimise

12

Found 168 words in 0.33513 seconds