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Yes, peyote is in the scrabble dictionary

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Peyote Definition

noun

A spineless, dome-shaped cactus (Lophophora williamsii) native to Mexico and the southwest United States, having buttonlike tubercles that are chewed fresh or dry as a narcotic drug by certain Native American peoples. Also called mescal.
from The American Heritage Dictionary of the English Language, 4th Edition
See mescal button.
from The American Heritage Dictionary of the English Language, 4th Edition
See mescaline.
from The American Heritage Dictionary of the English Language, 4th Edition
A hallucinogenic drug containing mescaline that is derived from peyote buttons and used especially in the religious ceremonies of some American Indian peoples.
from Free Scrabble Dictionary
A small low spineless cactus () of the southwestern United States and Mexico having rounded stems covered with jointed tubercles .
from Free Scrabble Dictionary

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Top Words by points

Points
peyote

11

2 letter words with PEYOTE

Points

po

4

to

2

te

2

ye

5

pe

4

yo

5

oy

5

op

4

oe

2

et

2

3 letter words with PEYOTE

Points

yep

8

yet

6

tye

6

toy

6

top

5

toe

3

tee

3

pye

8

pot

5

pet

5

pee

5

opt

5

ope

5

eye

6

4 letter words with PEYOTE

Points

poet

6

tope

6

tyee

7

type

9

typo

9

5 letter words with PEYOTE

Points

tepoy

10

topee

7

6 letter words with PEYOTE

Points

peyote

11

Found 32 words in 0.16474 seconds