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Yes, rune is in the scrabble dictionary

...and is worth 6 points by itself.

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Rune Definition

noun

A Finnish poem or section of a poem.
A poem or incantation of mysterious significance, especially a magic charm.
A similar character in another alphabet, sometimes believed to have magic powers.
Any of the characters in several alphabets used by ancient Germanic peoples from the 3rd to the 13th century.
Any of the characters of any of several alphabets used by the Germanic peoples from about the 3d to the 13th centuries.
source from Merriam-Webster

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Top Words by points

Points
rune

4

2 letter words with RUNE

Points

en

2

er

2

ne

2

nu

2

re

2

un

2

3 letter words with RUNE

Points

ern

3

rue

3

run

3

urn

3

4 letter words with RUNE

Points

rune

4

Found 11 words in 0.11466 seconds