Yes, serein is in the scrabble dictionary

...and is worth 7 points by itself.

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Serein Definition

noun

Light rainfall from a cloudless sky after sunset.
from the English-language Wiktionary

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Here are some other words you could make with the letters SEREIN, you can also
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Top Words by points

Points

nereis

6

2 letter words with SEREIN

Points

ne

2

si

2

en

2

re

2

is

2

in

2

er

2

es

2

3 letter words with SEREIN

Points

ens

3

see

3

sei

3

sen

3

ser

3

sin

3

sir

3

sri

3

rin

3

res

3

rei

3

ree

3

ers

3

nee

3

ire

3

ins

3

ere

3

ern

3

4 letter words with SEREIN

Points

seen

4

rins

4

seer

4

sene

4

sere

4

sine

4

sire

4

rise

4

reis

4

rein

4

rees

4

ires

4

esne

4

erns

4

erne

4

5 letter words with SEREIN

Points

rinse

5

sneer

5

siren

5

siree

5

serin

5

seine

5

ernes

5

reins

5

resin

5

risen

5

6 letter words with SEREIN

Points

nereis

6

seiner

6

serein

6

serine

6

Found 55 words in 0.17407 seconds