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Yes, serene is in the scrabble dictionary

...and is worth 7 points by itself.

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Serene Definition

noun

A serene condition or expanse (as of sky, sea, or light).
from Free Scrabble Dictionary

adjective

Unaffected by disturbance; calm and unruffled. See Synonyms at calm.
from The American Heritage Dictionary of the English Language, 4th Edition
Unclouded; fair: serene skies and a bright blue sea.
from The American Heritage Dictionary of the English Language, 4th Edition
Used as a title and form of address for certain members of royalty: Her Serene Highness; His Serene Highness.
from The American Heritage Dictionary of the English Language, 4th Edition
Clear and free of storms or unpleasant change .
from Free Scrabble Dictionary
Shining bright and steady .
from Free Scrabble Dictionary

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Top Words by points

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reseen

6

2 letter words with SERENE

Points

er

2

es

2

en

2

re

2

ne

2

3 letter words with SERENE

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ree

3

ser

3

sen

3

see

3

res

3

nee

3

ers

3

ens

3

ere

3

ern

3

4 letter words with SERENE

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esne

4

sere

4

sene

4

seer

4

seen

4

rees

4

erne

4

erns

4

5 letter words with SERENE

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resee

5

ernes

5

sneer

5

6 letter words with SERENE

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reseen

6

serene

6

Found 28 words in 0.17313 seconds