Yes, sister is in the scrabble dictionary

...and is worth 6 points by itself.

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Sister Definition

noun

A close woman friend or companion.
from The American Heritage Dictionary of the English Language, 4th Edition
A fellow African-American woman or girl.
from The American Heritage Dictionary of the English Language, 4th Edition
A fellow woman.
from The American Heritage Dictionary of the English Language, 4th Edition
A female having the same parents as another or one parent in common with another.
from The American Heritage Dictionary of the English Language, 4th Edition
A girl or woman who shares a common ancestry, allegiance, character, or purpose with another or others, specifically:.
from The American Heritage Dictionary of the English Language, 4th Edition

adjective

Genetics Of or being one of an identical pair: sister chromatids.
from The American Heritage Dictionary of the English Language, 4th Edition
Related by or as if by sisterhood; closely related: sister ships; sister cities.
from The American Heritage Dictionary of the English Language, 4th Edition

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Top Words by points

Points

resist

6

2 letter words with SISTER

Points

it

2

si

2

er

2

re

2

is

2

te

2

ti

2

et

2

es

2

3 letter words with SISTER

Points

tes

3

tie

3

set

3

sri

3

sit

3

sis

3

tis

3

sir

3

ser

3

sei

3

ers

3

ess

3

est

3

ire

3

its

3

rei

3

ret

3

res

3

4 letter words with SISTER

Points

sris

4

sire

4

sirs

4

site

4

sits

4

rise

4

stir

4

ests

4

erst

4

tier

4

ties

4

tire

4

sers

4

seis

4

ires

4

reis

4

rest

4

sets

4

rets

4

rite

4

5 letter words with SISTER

Points

tries

5

tress

5

tires

5

tiers

5

resit

5

rests

5

rises

5

rites

5

stirs

5

sties

5

sites

5

sires

5

6 letter words with SISTER

Points

resist

6

resits

6

sister

6

Found 62 words in 0.16349 seconds