Yes, siziest is in the scrabble dictionary

...and is worth 16 points by itself.

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Siziest Definition

See sizy.

from Free Scrabble Dictionary

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Here are some other words you could make with the letters SIZIEST, you can also
use this lookup tool to help you find words with our scrabble word finder.

Top Words by points	Points
siziest	16

2 letter words with SIZIEST	Points
et	2
te	2
ti	2
is	2
it	2
es	2
si	2

3 letter words with SIZIEST	Points
sei	3
zit	12
tes	3
tie	3
tis	3
sit	3
sis	3
set	3
its	3
tiz	12
est	3
ess	3

4 letter words with SIZIEST	Points
ties	4
zest	13
ziti	13
zits	13
size	13
sits	4
site	4
sets	4
seis	4
ests	4

5 letter words with SIZIEST	Points
zests	14
zitis	14
tizes	14
sties	5
sizes	14
sites	5
issei	5

7 letter words with SIZIEST	Points
siziest	16
sizeist	16

Found 38 words in 0.22907 seconds