Yes, slyer is in the scrabble dictionary

...and is worth 8 points by itself.

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Slyer Definition

adjective

Comparative form of sly.
from the English-language Wiktionary

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Wildcard(?) letters appear in RED

Here are some other words you could make with the letters SLYER, you can also
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Top Words by points

Points

lyres

8

2 letter words with SLYER

Points

er

2

es

2

el

2

ye

5

re

2

3 letter words with SLYER

Points

yes

6

sly

6

ser

3

sel

3

rye

6

res

3

lye

6

ley

6

ers

3

els

3

4 letter words with SLYER

Points

lyse

7

lyre

7

lyes

7

rely

7

ryes

7

leys

7

5 letter words with SLYER

Points

lyres

8

slyer

8

Found 23 words in 0.16032 seconds