Yes, spouse is in the scrabble dictionary

...and is worth 10 points by itself.

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Spouse Definition

noun

A marriage partner; a husband or wife.
from The American Heritage Dictionary of the English Language, 4th Edition
Married person .
from Free Scrabble Dictionary

verb-transitive

Archaic To marry; wed.
from The American Heritage Dictionary of the English Language, 4th Edition

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Top Words by points

Points

opuses

8

2 letter words with SPOUSE

Points

up

4

so

2

po

4

pe

4

us

2

os

2

op

4

oe

2

es

2

3 letter words with SPOUSE

Points

ups

5

upo

5

ess

3

sus

3

sup

5

sue

3

sou

3

use

3

sos

3

sop

5

oes

3

ope

5

ops

5

ose

3

pus

5

pos

5

pes

5

4 letter words with SPOUSE

Points

soup

6

uses

4

epos

6

sups

6

supe

6

sues

4

spue

6

sous

4

peso

6

seps

6

pose

6

puss

6

oses

4

opus

6

opes

6

sops

6

5 letter words with SPOUSE

Points

soups

7

souse

5

spues

7

supes

7

puses

7

posse

7

poses

7

pesos

7

6 letter words with SPOUSE

Points

opuses

8

spouse

8

Found 52 words in 0.16485 seconds