Yes, sure is in the scrabble dictionary

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Sure Definition

adjective

Bound to come about or happen; inevitable: sure defeat.
from The American Heritage Dictionary of the English Language, 4th Edition
Careful to do something: asked me to be sure to turn off the stove.
from The American Heritage Dictionary of the English Language, 4th Edition
Certain not to miss or err; steady: a sure hand on the throttle.
from The American Heritage Dictionary of the English Language, 4th Edition
Confident, as of something awaited or expected: sure of ultimate victory.
from The American Heritage Dictionary of the English Language, 4th Edition
Free from or marked by freedom from doubt: sure of her friends.
from The American Heritage Dictionary of the English Language, 4th Edition

adverb

Informal Surely; certainly.
from The American Heritage Dictionary of the English Language, 4th Edition

idiom

Make sure To establish something without doubt; make certain: Make sure he writes it down.
from The American Heritage Dictionary of the English Language, 4th Edition
Sure enough As one might have expected; certainly.
from The American Heritage Dictionary of the English Language, 4th Edition
To be sure Indeed; certainly.
from The American Heritage Dictionary of the English Language, 4th Edition

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Top Words by points

Points

rues

4

2 letter words with SURE

Points

er

2

es

2

re

2

us

2

3 letter words with SURE

Points

ers

3

res

3

rue

3

ser

3

sue

3

use

3

4 letter words with SURE

Points

rues

4

ruse

4

suer

4

sure

4

user

4

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