Yes, twyer is in the scrabble dictionary

...and is worth 10 points by itself.

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Twyer Definition

noun

Alternative spelling of tuyere.
from the English-language Wiktionary

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Here are some other words you could make with the letters TWYER, you can also
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Top Words by points

Points

twyer

11

2 letter words with TWYER

Points

et

2

ew

5

re

2

er

2

te

2

ye

5

we

5

3 letter words with TWYER

Points

yew

9

yet

6

wye

9

wry

9

wet

6

tye

6

try

6

tew

6

rye

6

ret

3

4 letter words with TWYER

Points

tyre

7

tyer

7

trey

7

wert

7

wyte

10

5 letter words with TWYER

Points

twyer

11

Found 23 words in 0.13888 seconds