Yes, uptime is in the scrabble dictionary

...and is worth 13 points by itself.

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Uptime Definition

noun

The time during which a device, such as a computer, is functioning or available for use.
from The American Heritage Dictionary of the English Language, 4th Edition
Time during which a piece of equipment (as a computer) is functioning or able to function.
from Free Scrabble Dictionary

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Top Words by points

Points

impute

10

2 letter words with UPTIME

Points

et

2

em

4

te

2

ti

2

pi

4

pe

4

mu

4

mi

4

me

4

um

4

up

4

it

2

ut

2

3 letter words with UPTIME

Points

tup

5

tum

5

tui

3

tip

5

tie

3

ump

7

ute

3

pit

5

put

5

piu

5

pie

5

pet

5

emu

5

mut

5

met

5

imp

7

4 letter words with UPTIME

Points

ptui

6

emit

6

etui

4

item

6

tump

8

time

6

temp

8

mite

6

mute

6

5 letter words with UPTIME

Points

tempi

9

6 letter words with UPTIME

Points

impute

10

uptime

10

Found 41 words in 0.21181 seconds